| Identifier |
19910225_nanos_researchpres_04 |
| Title |
Dopamine Blockade Has No Effect on the Human Flash ERG |
| Creator |
Mark J. Kupersmith, MD, Professor of Neuro-Ophthalmology Neurology Ophthalmology, Mount Sinai, New York, NY |
| Subject |
Dopaminergic Neurotransmission; Dopamine Blockade; Abnormal Contrast Sensitivity; Delayed Pattern Visual Evoked Potentials; Parkinson's Disease |
| Description |
Dopaminergic neurotransmission has been shown to modulate retinal processing in animal experiments. In humans, dopamine is found in interplexiform cells. Generalized disturbances of central nervous system dopaminergic function are associated with abnormal contrast sensitivity and delayed pattern visual evoked potentials. These visual system disturbances have been attributed to defects in retinal dopaminergic activity. We have previously shown that retinal function, as measured by the flash ERG (FERG), is normal in Parkinson's disease, a dopamine deficiency (1982). The current study shows that neither acute nor chronic administration of dopaminergic receptor blocking agents (with blockade of 01 , 02, or both receptors) has any significant effect on the FERG. |
| Date |
1991-02-25 |
| Language |
eng |
| Format |
application/pdf |
| Format Creation |
application/pdf |
| Type |
Text |
| Source |
1991 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS 1991: Research Presentations |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6j4205v |
| Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
| Contributor Primary |
Kupersmith, Mark J |
| Setname |
ehsl_novel_nam |
| ID |
183028 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6j4205v |
